G PROTEIN-COUPLED RECEPTORS IN DRUG DISCOVERY
G protein-coupled receptors (GPCRs) are the largest human membrane protein, family. These receptors play a diverse role in numerous physiological processes and possess ‘druggable’ sites making them an attractive pharmacological target. It is estimated that up to half of all marketed drugs act by binding to GPCRs.1,2 This infographic aims to summarize approved and novel drugs, GPCR targets, and indications.
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