Drug-Nutrient Interactions The impact of B vitamins on nonsteroidal anti-inflammatory drug efficacy and safety

Drug-nutrient interactions (DNAs) are defined as physical, chemical, physiologic or pathophysiologic relationships between a drug and a nutrient present in a food or a supplement. A DNI is considered clinically relevant when the pharmacokinetic or the pharmacodynamic response of a drug is altered, impacting drug and/or nutrient availability at various sites of action.
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