New insight into how Biogen's Tecfidera works may lead to better MS therapies

Biogen’s top-selling Tecfidera (dimethyl fumarate) has proven to be an effective treatment for multiple sclerosis, bringing in $4.27 billion in sales in 2018, but its exact mechanism of action remains a mystery. Now scientists from the City University of New York and the Icahn School of Medicine at Mount Sinai have identified a possible mechanism of action, providing information that they believe could lead to better drugs for MS and other autoimmune diseases.
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