Novartis' canakinumab failed to improve survival in Phase III trial

ZURICH (Reuters) - Novartis said on Tuesday its drug canakinumab (ACZ885) did not meet the primary endpoint of overall survival in patients with advanced or metastatic non-small cell lung cancer in a Phase III study, but other late-stage trials are ongoing. The Phase III CANOPY-2 study was evaluating canakinumab in combination with the chemotherapy agent docetaxel in 237 adults with non-small cell lung cancer whose disease progressed while on or after previous platinum-based chemotherapy.
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