Merck/Pfizer’s Bavencio flunks second ovarian cancer trial

Merck KGaA and Pfizer PD-L1 inhibitor Bavencio has missed the mark in its second ovarian cancer trial in a month, this time failing in previously-untreated patients. Results from a planned interim analysis of the phase III JAVELIN Ovarian 100 trial showed that Bavencio (avelumab) was unable to improve progression-free survival (PFS) compared to control groups when used as a maintenance therapy.
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